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Generic brand of avodart (the active ingredient is an anti-diarrhea medication). Bentley's own marketing documents make explicit the link between Avodart and ADHD. For example, the firm says: "Adverse events generic equivalent for avodart involving all-oral formulations have been infrequent to rare, occurring with a small percentage of patients." The firm has also been more open about the possible risks associated with Avodart on its websites. It says that "children with ADHD may experience some discomfort or gastrointestinal distress during the first week of Avodart treatment" and that "children adults with ADHD and Avodart may experience stomach upset during the first few weeks." What's more, the manufacturer has repeatedly claimed that "most people with ADHD use a drug or two for attention deficit disorders." In its 2010 submission to the US Food and Drug Administration, it listed five types of drugs that it says are used to treat ADHD: amphetamines, barbiturates, antihistamines, nonsteroidal anti-inflammatory drugs, and some antidepressants. None, it says, should be used alone. A large survey of ADHD practitioners, published in 2011 the American Journal of Psychiatry, found there was "strong agreement" among ADHD specialists that combining medications from several classes could be dangerous for ADHD patients. The FDA received reports of 11 serious side effects related to Avodart (including heart problems, skin damage and liver infections) between 1989 2005 "related to use of Avodart treat ADHD," the report says. At least two of the reports "involved adverse reactions that were considered related to the ADHD medication" and included details of "severe liver problems." A 2010 study in JAMA Pediatrics, "Adverse effects," found that in over 200,000 children who took an average of 12.9mg ADHD medication daily, 13 reported one or more adverse health effects while taking the drug. All but five of those who experienced adverse effects were on the stronger 2mg/day version of Avodart. The study also found that ADHD "associated adverse events are primarily mild and infrequent in nature." The "very large" (5.8 million children) 2009 study of children under the age five in Great Britain concluded that children taking ADHD medication "were at risk of adverse events." Among those, 7.4% experienced an adverse event while taking ADHD medication, 0.8% experienced one or more serious side effects while taking a drug that targets the same neurons. The FDA received avodart generic usa reports of 11 serious side effects related to Avodart (including heart problems, skin damage and liver infections) between 1989 2005 related to use of Avodart treat ADHD In fact, Avodart has "much higher" risks than any other drug studied for the disorder, says Dr Richard Hulme, a consultant psychiatrist in Birmingham, England. He co-led a 2003 study that concluded "it is possible for serious adverse events due to the use of anticonvulsants occur." He has published a more recent report that found "adverse events related to [ADHD medications] are more likely to be reported in adults with ADHD than children." In another 2010 report Pediatrics, pediatricians warned that "overuse of medications" could cause "serious harm" and called for tighter restrictions on how ADHD drugs should be prescribed. "Overdoses with certain stimulants have been observed," the authors wrote. The FDA has not taken any action against brands of Avodart in the United States that have been found in children's cases to be unsafe. At least two manufacturers also remain on the US market, as do dozens of generic manufacturers. The American Academy of Child and Adolescent Psychiatry the US Food and Drug Administration declined an interview request for this article. A spokeswoman Avodart, Heather Bekar, wrote in an email that Avodart "has had zero issues on the national market from children. In Canada, the product has not been approved by Health Canada and is currently not allowed to be imported in over half of Canadian provinces." When asked about the safety Antabuse availability in australia of Avodart in United States, the FDA's Bekar told BMJ: "We don't comment on products in development." So parents can find out what to expect if they take a brand-name medication for the disorder, but not what they should do if choose a generic version that they haven't heard about. The FDA doesn't have a comprehensive list of ADHD generic manufacturers. But according to an online database maintained by the website PharmacyChecker.com, most common generic variants are Janssen Pharmaceuticals Inc's Provigil and Mylan Epinephrine Injection. In October, the company behind Epinephrine, Sanofi-Aventis, announced a new $1.5 billion round of funding that valued it at.



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Project:          Terminal 5 logistics
Client:            Amec
Timescale:     4 years
Value:            £3M

Works carried out:

T. A. Ronan & Co. carried out the cable installation, jointing and associated trenching and duct laying for the LV site temporaries throughout the Terminal 5 construction site. This included the moving of temporary substations as the construction site developed.

Completed the installation and maintenance of the semi-permanent street lighting and flood lighting from 18-metre towers, including the erection of the towers and street lights.